Hepatic Cannabinoid Signaling in the Regulation of Alcohol-Associated Liver Disease
Abstract PURPOSE: The endocannabinoid system has emerged as a key regulatory signaling pathway in the pathophysiology of alcohol-associated liver disease…
Review Article
Recent Updates and Advances in Winiwarter-Buerger Disease (Thromboangiitis Obliterans): Biomolecular Mechanisms, Diagnostics and Clinical Consequences
Abstract Thromboangiitis obliterans (TAO) or Buerger’s disease is a segmental inflammatory, thrombotic occlusive peripheral vascular disease with unknown aetiology that…
Cannabis Glandular Trichomes: A Cellular Metabolite Factory
Abstract Cannabis has been legalized for recreational use in several countries and medical use is authorized in an expanding list…
Cannabinoids—A New Perspective in Adjuvant Therapy for Pulmonary Hypertension
Abstract Currently, no treatment can completely cure pulmonary hypertension (PH), which can lead to right ventricular failure and, consequently, death.…
Neurofibromatosis: Molecular Pathogenesis and Natural Compounds as Potential Treatments
Abstract The neurofibromatosis syndromes, including NF1, NF2, and schwannomatosis, are tumor suppressor syndromes characterized by multiple nervous system tumors, particularly…
The Endocannabinoid System and Cannabidiol: Past, Present, and Prospective for Cardiovascular Diseases
Abstract In the past, cannabis was commonly associated with mysticism and illegality. Fortunately, in recent years perspectives and discourses have…
The Development of Pharmacological Therapies for Alzheimer’s Disease
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that currently has no cure. The aged population is growing globally,…
Effects of Cannabinoid Exposure during Neurodevelopment on Future Effects of Drugs of Abuse: A Preclinical Perspective
Abstract The endocannabinoid system plays a central role in the earliest stages of embryonic, postnatal and adolescent neurodevelopment. Aberrant activity…
Understanding the Modulatory Effects of Cannabidiol on Alzheimer’s Disease
Abstract Alzheimer’s disease (AD), the most common neurodegenerative disease, is characterized by progressive cognitive impairment. The deposition of amyloid beta…
Cannabis and Athletic Performance
Abstract Cannabis is widely used for both recreational and medicinal purposes on a global scale. There is accumulating interest in…