Epigenetic Studies for Evaluation of NPS Toxicity: Focus on Synthetic Cannabinoids and Cathinones
Abstract In the recent decade, numerous new psychoactive substances (NPSs) have been added to the illicit drug market. These are…
Review Article
Heterogeneous data integration methods for patient similarity networks
Abstract Patient similarity networks (PSNs), where patients are represented as nodes and their similarities as weighted edges, are being increasingly…
Neuropathology and emerging biomarkers in corticobasal syndrome
Abstract Corticobasal syndrome (CBS) is a clinical syndrome characterised by progressive asymmetric limb rigidity and apraxia with dystonia, myoclonus, cortical…
Characterization of Severity in Zellweger Spectrum Disorder by Clinical Findings: A Scoping Review, Meta-Analysis and Medical Chart Review
Abstract Zellweger spectrum disorder (ZSD) is a rare, debilitating genetic disorder of peroxisome biogenesis that affects multiple organ systems and…
Dietary PUFAs and Exercise Dynamic Actions on Endocannabinoids in Brain: Consequences for Neural Plasticity and Neuroinflammation
Abstract The brain and peripheral nervous system provide oversight to muscle physiology and metabolism. Muscle is the largest organ in…
Cross-Talk between the (Endo)Cannabinoid and Renin-Angiotensin Systems: Basic Evidence and Potential Therapeutic Significance
Abstract This review is dedicated to the cross-talk between the (endo)cannabinoid and renin angiotensin systems (RAS). Activation of AT1 receptors…
The Endocannabinoids-Microbiota Partnership in Gut-Brain Axis Homeostasis: Implications for Autism Spectrum Disorders
Abstract The latest years have witnessed a growing interest towards the relationship between neuropsychiatric disease in children with autism spectrum…
Cannabinoids as Glial Cell Modulators in Ischemic Stroke: Implications for Neuroprotection
Abstract Stroke is the second leading cause of death worldwide following coronary heart disease. Despite significant efforts to find effective…
Involvement of the cannabinoid system in chronic inflammatory intestinal diseases: opportunities for new therapies
Abstract The components of the endogenous cannabinoid system are widely expressed in the gastrointestinal tract contributing to local homeostasis. In…
Lipid-Drug Conjugates and Nanoparticles for the Cutaneous Delivery of Cannabidiol
Abstract Lipid nanoparticles are currently used to deliver drugs to specific sites in the body, known as targeted therapy. Conjugates…