The safety and efficacy of low oral doses of cannabidiol: An evaluation of the evidence
Abstract Global interest in the non‐intoxicating cannabis constituent, cannabidiol (CBD), is increasing with claims of therapeutic effects across a diversity…
Review Article
Canadian Resources on Cannabis Use and Fertility, Pregnancy, and Lactation: Scoping Review
Abstract Background: Cannabis use among reproductive-aged Canadians is increasing, but our understanding of its impacts on fertility, pregnancy, and breast…
Intracellular Molecular Targets and Signaling Pathways Involved in Antioxidative and Neuroprotective Effects of Cannabinoids in Neurodegenerative Conditions
Abstract In the last few decades, endocannabinoids, plant-derived cannabinoids and synthetic cannabinoids have received growing interest as treatment options in…
Cannabidiol in Dentistry: A Scoping Review
Abstract Cannabidiol (CBD) has been gaining increased attention in contemporary society but seems to have been little explored in dentistry.…
Neutral CB1 Receptor Antagonists as Pharmacotherapies for Substance Use Disorders: Rationale, Evidence, and Challenge
Abstract Cannabinoid receptor 1 (CB1R) has been one of the major targets in medication development for treating substance use disorders…
Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration–effect relations using the IB-de-risk tool
Abstract Background: Preclinical research suggests that cannabidiol (CBD) may have therapeutic potential in pathological anxiety. Dosing guidelines to inform future…
Regulation of transient receptor potential channels by traditional Chinese medicines and their active ingredients
Abstract In recent years, activation of thermal transient receptor potential (TRP) ion channels at a range of temperatures has received…
Applications of Hemp Polymers and Extracts in Food, Textile and Packaging: A Review
Abstract Hemp (Cannabis sativa Linn.) is a high-yielding annual crop farmed for its stalk fiber and oil-producing seeds. This specialized…
Peripheral biomarkers of treatment-resistant schizophrenia: Genetic, inflammation and stress perspectives
Abstract Treatment-resistant schizophrenia (TRS) often results in severe disability and functional impairment. Currently, the diagnosis of TRS is largely exclusionary…
The impact of phyto- and endo-cannabinoids on central nervous system diseases：A review
Abstract Background and aim: Cannabis sativa L. is a medicinal plant with a long history. Phyto-cannabinoids are a class of…