Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives
Abstract Cannabigerol (CBG) is a cannabinoid from the plant Cannabis sativa that lacks psychotomimetic effects. Its precursor is the acidic…
Review Article
Astrocytes as a Therapeutic Target in Alzheimer’s Disease–Comprehensive Review and Recent Developments
Abstract Alzheimer’s disease (AD) is a frequent and disabling neurodegenerative disorder, in which astrocytes participate in several pathophysiological processes including…
The value of real world evidence: The case of medical cannabis
Abstract Randomised controlled trials (RCTs) have long been considered the gold standard of medical evidence. In relation to cannabis based…
Molecular Pathways of the Therapeutic Effects of Ayahuasca, a Botanical Psychedelic and Potential Rapid-Acting Antidepressant
Abstract Ayahuasca is a psychoactive brew traditionally used in indigenous and religious rituals and ceremonies in South America for its…
The role of dopamine and endocannabinoid systems in prefrontal cortex development: Adolescence as a critical period
Abstract The prefrontal cortex plays a central role in the control of complex cognitive processes including action control and decision…
The Efficacy of Psychedelic-Assisted Therapy in Managing Post-traumatic Stress Disorder (PTSD): A New Frontier?
Abstract Post-traumatic stress disorder (PTSD) is a significant public health concern for which existing therapies are only marginally effective. Indisputably,…
Recent Advances in Endocannabinoid System Targeting for Improved Specificity: Strategic Approaches to Targeted Drug Delivery
Abstract Opportunities for developing innovative and intelligent drug delivery technologies by targeting the endocannabinoid system are becoming more apparent. This…
Toxicological Findings of Self-Poisoning Suicidal Deaths: A Systematic Review by Countries
Abstract The use of illicit and non-illicit substances is widespread in suicides. The toxicological data may help in understanding the…
Trends in Substance Use and Abuse During COVID-19 Among the General Population
Abstract Background: COVID-19 pandemic has brought many public health issues, including substance use and abuse. Individuals abusing substances are vulnerable…
Cannabinol: History, Syntheses, and Biological Profile of the Greatest “Minor” Cannabinoid
Abstract Cannabis (Cannabis sativa L.) is an outstanding source of bioactive natural products, with more than 150 different phytocannabinoids isolated…