Structural and functional insights into the G protein-coupled receptors: CB1 and CB2
Abstract The cannabinoid receptors CB1 and CB2 mediate a variety of physiological processes and continue to be explored as desirable…
Review Article
Is Cannabis Effective in the Treatment of Chronic Back Pain?
Abstract Cannabis is commonly recognized as a recreational substance. It has been explored for its potential therapeutic applications in addressing…
Molecular and Cellular Mechanisms of Action of Cannabidiol
Abstract Cannabidiol (CBD) is the primary non-psychoactive chemical from Cannabis Sativa, a plant used for centuries for both recreational and…
A systematic review of economic evaluations for opioid misuse, cannabis and illicit drug use prevention
Abstract Background: Substance use disorders negatively affect global disease burden. Effective preventive interventions are available, but whether they provide value…
Cannabinoids in the treatment of cancer anorexia and cachexia: Where have we been, where are we going?
Abstract Cachexia–anorexia cancer syndrome remains an unmet clinical need with a dearth of treatment and no standard of care. Acting…
Role of TRP Channels in Liver-Related Diseases
Abstract The liver plays a crucial role in preserving the homeostasis of an entire organism by metabolizing both endogenous and…
Biobehavioral Interactions between Endocannabinoid and Hypothalamic-pituitary-adrenal Systems in Psychosis: A Systematic Review
Abstract Background: The diathesis-stress paradigm and the cannabinoid-hypothesis have been proposed as possible pathophysiological models of schizophrenia. However, they have…
Candida Biofilm Eye Infection: Main Aspects and Advance in Novel Agents as Potential Source of Treatment
Abstract Fungi represent a very important cause of microbial eye infections, especially in tropical and developing countries, as they could…
Update on neurobiological mechanisms of fear: illuminating the direction of mechanism exploration and treatment development of trauma and fear-related disorders
Abstract Fear refers to an adaptive response in the face of danger, and the formed fear memory acts as a…
Could cannabinoids provide a new hope for ovarian cancer patients?
Abstract It is known that gynecological cancers remain a worldwide problem and as shown by the statistics, there is a…