Financial Burden of Drugs Prescribed for Cancer-Associated Symptoms
Abstract METHODS: We reviewed relevant guidelines and compiled drugs used to manage seven cancer-associated symptoms (anorexia and cachexia, chemotherapy-induced peripheral…
Research Article
Public health monitoring of cannabis use in Europe: prevalence of use, cannabis potency, and treatment rates
Abstract Background: Cannabis is one of the most widely used substances worldwide. Heavy use is associated with an increased risk…
Computational Approach Reveals Pronociceptive Potential of Cannabidiol in Osteoarthritis: Role of Transient Receptor Potential Channels
Abstract Systems pharmacology employs computational and mathematical methods to study the network of interactions a drug may have within complex…
Synthesis, characterization and stress-testing of a robust quillaja saponin stabilized oil-in-water phytocannabinoid nanoemulsion
Abstract Background: This study describes the design, optimization, and stress-testing of a novel phytocannabinoid nanoemulsion generated using high-pressure homogenization. \(\text…
Effect of Varying Levels of Hempseed Meal Supplementation on Humoral and Cell-Mediated Immune Responses of Goats
Abstract Simple Summary: Hempseed meal (HSM) is a byproduct of hemp oil production and is high in protein, fiber, and…
Pharmacogenetic Predictors of Cannabidiol Response and Tolerability in Treatment‐Resistant Epilepsy
Abstract In patients with treatment‐resistant epilepsy (TRE), cannabidiol (CBD) produces variable improvement in seizure control. Patients in the University of…
Cellular distribution of cannabinoid‐related receptors TRPV1, PPAR‐gamma, GPR55 and GPR3 in the equine cervical dorsal root ganglia
Abstract Background: The activation of cannabinoid and cannabinoid‐related receptors by endogenous, plant‐derived or synthetic cannabinoids may exert beneficial effects on…
CBD Alleviates Liver Injuries in Alcoholics With High-Fat High-Cholesterol Diet Through Regulating NLRP3 Inflammasome–Pyroptosis Pathway
Abstract Alcohol abuse and high-fat diet–induced liver diseases have been the most prevalent chronic liver diseases and the leading reasons…
In silico analysis enabling informed design for genome editing in medicinal cannabis; gene families and variant characterisation
Abstract Background: Cannabis has been used worldwide for centuries for industrial, recreational and medicinal use, however, to date no successful…
Identification of BiP as a CB1 Receptor-Interacting Protein That Fine-Tunes Cannabinoid Signaling in the Mouse Brain
Abstract Cannabinoids, the bioactive constituents of cannabis, exert a wide array of effects on the brain by engaging Type 1…