Theoretical and Therapeutic Implications of the Spasticity-Plus Syndrome Model in Multiple Sclerosis
Abstract In patients with multiple sclerosis (MS), a typical pattern of muscle tone alteration, known as spasticity, is frequently observed…
Research Article
Adolescent E-cigarette or Vaping Use-Associated Lung Injury in the Delaware Valley: A Review of Hospital-Based Presentation, Management, and Outcomes
Abstract E-cigarette or vaping use-associated lung injury (EVALI) remains a major concern due to ongoing use of nicotine and/or cannabis-containing…
Use of computational toxicology tools to predict in vivo endpoints associated with Mode of Action and the endocannabinoid system: A case study with chlorpyrifos, chlorpyrifos-oxon and Δ9Tetrahydrocannabinol
Keywords: Chlorpyrifos, Chlorpyrifos-oxon, High throughput toxicokinetics, HTTK-Pop, ToxCast/Tox21, Pop, Population, HTTK:, High throughput toxicokinetics, ToxCast/Tox21, CompTox Chemicals Dashboard High throughput…
Physicochemical and Functional Properties of 2S, 7S, and 11S Enriched Hemp Seed Protein Fractions
Abstract The hemp seed contains protein fractions that could serve as useful ingredients for food product development. However, utilization of…
Understanding the Placental Biology of Tobacco Smoke, Nicotine, and Marijuana (THC) Exposures During Pregnancy
Abstract Widespread public health campaigns have reduces the prevalence of tobacco and nicotine exposures during pregnancy in the United States.…
Cannabinoid and substance relationships of European congenital anomaly patterns: a space-time panel regression and causal inferential study
Abstract With reports from Australia, Canada, USA, Hawaii and Colorado documenting a link between cannabis and congenital anomalies (CAs), this…
A Cannabinoid 2-Selective Agonist Inhibits Allogeneic Skin Graft Rejection In Vivo
Abstract Previous work from our laboratory showed that a CB2 selective agonist, O-1966, blocked the proliferative response of C57BL/6 mouse…
Cannabidiol Inhibits Multiple Ion Channels in Rabbit Ventricular Cardiomyocytes
Abstract Cannabidiol (CBD), a major non-psychotropic cannabinoid found in the Cannabis plant, has been shown to exert anti-nociceptive, anti-psychotic, and…
Characterization and Biological Activity of Fiber-Type Cannabis sativa L. Aerial Parts at Different Growth Stages
Abstract Currently, there is a renewed interest in cannabis-related products in different fields because of the rich phytocomplex of this…
Comparison of the Effectiveness and Tolerability of Nabiximols (THC:CBD) Oromucosal Spray versus Oral Dronabinol (THC) as Add-on Treatment for Severe Neuropathic Pain in Real-World Clinical Practice: Retrospective Analysis of the German Pain e-Registry
Abstract Purpose: To compare the effectiveness and tolerability of add-on treatment with nabiximols (NBX: delta-9-tetrahydrocannabinol: cannabidiol) oromucosal spray or oral…