Sociodemographic differences in patterns of nicotine and cannabis vaping among US adults
Abstract About half (54.2%) of adults who used electronic vapor products (EVPs) vaped nicotine only. Only 7.4% of adults who…
Research Article
Determination of Prenatal Substance Exposure Using Meconium and Orbitrap Mass Spectrometry
Abstract The aim of this study was to develop and to validate a toxicological untargeted screening relying on LC-HRMS in…
GPR18-Mediated Relaxation of Human Isolated Pulmonary Arteries
Abstract GPR18 receptor protein was detected in the heart and vasculature and appears to play a functional role in the…
Metabolites of Cannabis Induce Cardiac Toxicity and Morphological Alterations in Cardiac Myocytes
Abstract Cannabis is one of the most commonly used recreational drugs worldwide. Rrecent epidemiology studies have linked increased cardiac complications…
Cannabidiol Increases Seizure Resistance and Improves Behavior in an Scn8a Mouse Model
Abstract Voltage-gated sodium channel genes are an important family of human epilepsy genes. De novo missense mutations in SCN8A (encoding…
Berberine Alleviate Cisplatin-Induced Peripheral Neuropathy by Modulating Inflammation Signal via TRPV1
Abstract Chemotherapy induced peripheral neuropathy (CIPN) is a severe neurodegenerative disorder caused by chemotherapy drugs. Berberine is a natural monomer…
Tobacco Rattle Virus as a Tool for Rapid Reverse-Genetics Screens and Analysis of Gene Function in Cannabis sativa L.
Abstract Medical cannabis (Cannabis sativa L.) is quickly becoming a central agricultural crop as its production has continued to increase…
Driving Performance and Cannabis Users’ Perception of Safety
Abstract This randomized clinical trial studies the magnitude and time course of effects of cannabis on driving, effect of cannabis…
Characterisation of Hemp Fibres Reinforced Composites Using Thermoplastic Polymers as Matrices
Abstract Hemp fibres used as a reinforcing agent and three polymeric matrices (polypropylene, bicomponent, recycled polyester) were used to obtain…
Polysubstance Use Patterns Among High Dose Benzodiazepine Users: A Latent Class Analysis and Differences Between Male and Female Use
Abstract Benzodiazepines (BZDs) represent one of the most widely used groups of pharmaceuticals, but if used for long periods of…