Reprogramming systemic and local immune function to empower immunotherapy against glioblastoma
Abstract The limited benefits of immunotherapy against glioblastoma (GBM) is closely related to the paucity of T cells in brain…
Research Article
State Cannabis Legalization and Psychosis-Related Health Care Utilization
Abstract This cohort study investigates whether state cannabis legalization is associated with psychosis-related healthcare utilization. Authors: Holly Elser, Keith Humphreys,…
Cannabidiol and Cannabigerol Exert Antimicrobial Activity without Compromising Skin Microbiota
Abstract Cannabidiol (CBD) and cannabigerol (CBG) are two pharmacologically active phytocannabinoids of Cannabis sativa L. Their antimicrobial activity needs further…
Determining the impact of cannabis use and severity on tobacco cessation outcomes: study protocol for a prospective tobacco treatment trial
Abstract Background: Several evidence-based tobacco cessation treatment strategies exist, though significant barriers to cessation remain which must be addressed to…
Properties of Sound Absorption Composite Materials Developed Using Flax Fiber, Sphagnum Moss, Vermiculite, and Sapropel
Abstract To address the need to reduce consumption and pollution in the industrial sector, composite materials were created using a…
Multi-Targeting Intranasal Nanoformulation as a Therapeutic for Alzheimer’s Disease
Abstract Melatonin, insulin, and Δ9-tetrahydrocannabinol (THC) have been shown to reverse cognitive deficits and attenuate neuropathologies in transgenic mouse models…
Chronic low-dose Δ9-tetrahydrocannabinol (THC) treatment stabilizes dendritic spines in 18-month-old mice
Abstract Cognitive functions decline during aging. This decline could be caused by changes in dendritic spine stability and altered spine…
Film Forming Systems for Delivery of Active Molecules into and across the Skin
Abstract We have investigated delivery systems that can form a structured matrix film on the skin after their application. In…
Identification of Novel CB2 Ligands through Virtual Screening and In Vitro Evaluation
Abstract Cannabinoid receptor type 2 (CB2) is a very promising therapeutic target for a variety of potential indications. However, despite…
Chiral Separation of Cannabichromene, Cannabicyclol, and Their Acidic Analogs on Polysaccharide Chiral Stationary Phases
Abstract Until recently, chirality has not been a major focus in the study of cannabinoids, as most cannabinoids of interest,…