Calculating the Aqueous pKa of Phenols: Predictions for Antioxidants and Cannabinoids
Abstract We aim to develop a theoretical methodology for the accurate aqueous pKa prediction of structurally complex phenolic antioxidants and…
Research Article
Prevalence of common mental disorders and associated factors among adults living in Harari regional state, eastern Ethiopia: a community based cross-sectional study
Abstract Background: Common mental disorders are highly prevalent in the population, affecting people across all regions of the world. In…
A pharmacist-led community-based survey study: Determining the impact of the Covid-19 pandemic on actionable factors associated with worse cancer outcomes and cancer health disparities
Abstract Purpose: The goals of this cross-sectional community-based survey study were to assess the impact of the Covid-19 pandemic on…
The pharmacology and therapeutic role of cannabidiol in diabetes
Abstract In recent years, cannabidiol (CBD), a non‐psychotropic cannabinoid, has garnered substantial interest in drug development due to its broad…
Cannabis sativa demonstrates anti-hepatocellular carcinoma potentials in animal model: in silico and in vivo studies of the involvement of Akt
Abstract Background: Targeting protein kinase B (Akt) and its downstream signaling proteins are promising options in designing novel and potent…
Chronic Pain, Cannabis Legalization and Cannabis Use Disorder in Veterans Health Administration Patients, 2005 to 2019
Abstract Background: The risk for cannabis use disorder (CUD) is elevated among U.S. adults with chronic pain, and CUD rates…
Conflicting forces in the implementation of medicinal cannabis regulation in Uruguay
Abstract Background: Uruguay is widely known as a pioneer country regarding cannabis regulation policies, as it was the first state…
Psychoactive substance use in patients diagnosed with attention-deficit/hyperactivity disorder: an exploratory study
Abstract Introduction: Attention-deficit/hyperactivity disorder (ADHD) was originally treated as a neurodevelopmental disorder that occurs mainly in children and tends to…
Expression of the endocannabinoid system and response to cannabinoid components by the human fetal testis
Abstract Background: Cannabis consumption by pregnant women continues to increase worldwide, raising concerns about adverse effects on fetal growth and…
Fetal cannabidiol (CBD) exposure alters thermal pain sensitivity, problem-solving, and prefrontal cortex excitability
Abstract Thousands of people suffer from nausea with pregnancy each year. Nausea can be alleviated with cannabidiol (CBD), a primary…