Effect of Cannabidiol on Human Peripheral Blood Mononuclear Cells and CD4+ T Cells
Abstract Cannabidiol (CBD), the main non-psychoactive component of Cannabis sativa L., is widely used in therapy for the treatment of…
Research Article
Substance Use and Educational Impacts in Youth With and Without Chronic Illness
Abstract Introduction: Alcohol, cannabis, and nicotine are commonly used psychoactive substances that affect adolescent neurocognition. Little is known about the…
GPR55 is expressed in glutamate neurons and functionally modulates nicotine taking and seeking in rats and mice
Abstract Cannabis legalization continues to progress in the USA for medical and recreational purposes. G protein-coupled receptor 55 (GPR55) is…
Development, Characterization and Pharmacological Evaluation of Cannabidiol-Loaded Long Circulating Niosomes
Abstract Cannabidiol (CBD) is a promising drug candidate with pleiotropic pharmacological activity, whose low aqueous solubility and unfavorable pharmacokinetics have…
Medical Cannabis Is Not Associated with a Decrease in Activities of Daily Living in Older Adults
Abstract The proportion of older adults using medical cannabis is rising. Therefore, we aimed to assess the effects of herbal…
Interaction of Synthetic Cannabinoid Receptor Agonists with Cannabinoid Receptor I: Insights into Activation Molecular Mechanism
Abstract Synthetic cannabinoid receptor agonists (SCRAs) have become a wide group of new psychoactive substances since the 2010s. For the…
Consumer perception, knowledge, and uses of cannabidiol
Abstract Introduction: The legalization of cannabidiol (CBD) across the United States, in varying degrees, has made CBD easily accessible to…
Metabolic memory of Δ9-tetrahydrocannabinol exposure in pluripotent stem cells and primordial germ cells-like cells
Abstract Cannabis, the most consumed illicit psychoactive drug in the world, is increasingly used by pregnant women. However, while cannabinoid…
Cannabidiol-Loaded Lipid-Stabilized Nanoparticles Alleviate Psoriasis Severity in Mice: A New Approach for Improved Topical Drug Delivery
Abstract Cannabidiol (CBD) is a promising natural agent for treating psoriasis. CBD activity is attributed to inhibition of NF-kB, IL-1β,…
Recreational cannabis legalization has had limited effects on a wide range of adult psychiatric and psychosocial outcomes
Abstract Background: The causal impacts of recreational cannabis legalization are not well understood due to the number of potential confounds.…