Harnessing Sex Reversion via Chemical Intervention in Cannabis sativa L.
Abstract Cannabis sativa is a multipurpose dioecious species whose crop performance is governed by sex expression. Although sex is genetically…
Research Article
ADAMDEC1 predicts prognosis and immunotherapy response in a pan-cancer study with experimental validation
Abstract Background: ADAMDEC1 (a disintegrin and metalloproteinase domain-like protein decysin-1) is linked to immune disorders and cancers, but its pan-cancer…
Identification and molecular typing of disulfidptosis-related biomarkers in anaplastic thyroid carcinoma
Abstract Increasing evidence suggests that disulfidptosis plays a crucial role in tumorigenesis and progression. This study aimed to identify biomarkers…
Hsa_circ_0002111 implicates KTC-1 cell motility and modulates migration and invasion via miR-432-5p/CDKN2B axis
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-49341-1. Article type: Research Article Keywords: hsa_circ_0002111, miR-432-5p, CDKN2B,…
Acute anti-proliferative and anti-migratory effects of cannabidiol on C6 rat glioma, SH-SY5Y human neuroblastoma, and HT22 mouse hippocampal neuronal cell cultures
Abstract Background: The treatment of central nervous system tumors remains challenging owing to their highly proliferative nature, aggressiveness, and poor…
Cannabis flower crude extracts as belowground infochemicals shaping the chemotactic responses of parasitic nematodes
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-49877-2. Article type: Research Article Keywords: Chemotaxis, Entomopathogenic nematodes,…
Steroid Hormone Changes after Short-Term High-Dose Exposure to Cannabidiol in Healthy Subjects: An Exploratory Study
Abstract Introduction: Cannabis-derived cannabidiol (CBD; Epidiolex®) is FDA-approved for seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, and tuberous sclerosis complex,…
Sodium Stearate-Assisted Optimization of a Cannabidiol Dry Powder Inhaler for Enhanced Dissolution and Aerosol Performance
Abstract Background/Objectives: Cannabidiol (CBD) has emerged as a potential therapeutic agent for respiratory disorders, including asthma and chronic obstructive pulmonary…
The greater the pleiotropic effects, the greater the benefits – cannabis as a “biopsychosocial” drug: a mixed-methods study on chronic non-cancer pain
Abstract Background: Against the background of widely inconsistent data from randomized controlled trials (RCT), the use of cannabis-based medicines (CBM)…
What Cues Do Laypeople Use to Detect Alcohol and Cannabis Intoxication?
Abstract Introduction: Alcohol and other drug use is common in Australia, yet laypeople struggle to detect intoxication in others via…