Medicinal Use of Different Cannabis Strains: Results from a Large Prospective Survey in Germany
Abstract Background Up to now, it is unclear whether different medicinal cannabis (MC) strains are differently efficacious across different medical…
Research Article
Sex Differences in the Acute Effects of Oral THC: A Randomized, Placebo-Controlled, Crossover Human Laboratory Study
Abstract Rationale: Recent reports have shown increased cannabis use among women, leading to growing concerns about cannabis use disorder (CUD).…
Using biochar for environmental recovery and boosting the yield of valuable non-food crops: The case of hemp in a soil contaminated by potentially toxic elements (PTEs)
Abstract Hemp (Cannabis sativa L.) is known to tolerate high concentrations of soil contaminants which however can limit its biomass…
Medicinal cannabis for treating post-traumatic stress disorder and comorbid depression: real-world evidence
Abstract Background: Cannabis-based medicinal products (CBMPs) are increasingly being used to treat post-traumatic stress disorder (PTSD), despite limited evidence of…
Cannabidiol Disrupts Mitochondrial Respiration and Metabolism and Dysregulates Trophoblast Cell Differentiation
Abstract Trophoblast differentiation is a crucial process in the formation of the placenta where cytotrophoblasts (CTs) differentiate and fuse to…
Oral Cannabidiol for Seborrheic Dermatitis in Patients With Parkinson Disease: Randomized Clinical Trial
Abstract Background: Seborrheic dermatitis (SD) affects 18.6%-59% of persons with Parkinson disease (PD), and recent studies provide evidence that oral…
Parliamentary question: Insights from the Federal National Council in the UAE
Abstract This paper highlights the paramount role of parliamentary questioning as a control mechanism exercised by the Federal National Council…
Theoretical Insights into the Gas-Phase Oxidation of 3-Methyl-2-butene-1-thiol by the OH Radical: Thermochemical and Kinetic Analysis
Abstract 3-Methyl-2-butene-1-thiol ((CH3)2C=CH–CH2–SH; MBT) is a recently identified volatile organosulfur compound emitted from Cannabis sativa and is purported to contribute…
Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists
Abstract We report a blueprint for the rational design of G protein coupled receptor (GPCR) ligands with a tailored functional…
Classical cannabinoid receptors as target in cancer-induced bone pain: a systematic review, meta-analysis and bioinformatics validation
Abstract To test the hypothesis that genetic and pharmacological modulation of the classical cannabinoid type 1 (CB1) and 2 (CB2)…