CDCM: a correlation-dependent connectivity map approach to rapidly screen drugs during outbreaks of infectious diseases
Abstract In the context of the global damage caused by coronavirus disease 2019 (COVID-19) and the emergence of the monkeypox…
Research Article
Sterol regulatory element binding transcription factor 1 is an important prognostic factor for colon adenocarcinoma and closely related to immune infiltration
Abstract Objective: Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) encodes a core protein that has a crucial function in…
The Anticancer Activity of Cannabinol (CBN) and Cannabigerol (CBG) on Acute Myeloid Leukemia Cells
Abstract Several cannabis plant-derived compounds, especially cannabinoids, exhibit therapeutic potential in numerous diseases and conditions. In particular, THC and CBD…
PTEN inhibits epithelial mesenchymal transition of thyroid cancer cells by regulating the Wnt/β-Catenin signaling pathway
Abstract Objective: The global incidence of thyroid cancer (THCA) has significantly risen in recent years. This study aims to investigate…
Cannabichromene as a Novel Inhibitor of Th2 Cytokine and JAK/STAT Pathway Activation in Atopic Dermatitis Models
Abstract Cannabichromene (CBC) is one of the main cannabinoids found in the cannabis plant, and although less well known than…
Synergistic Pain-Reducing Effects of Bixa orellana (Chronic® and Chronic In®) and Cannabidiol-Rich Cannabis sativa Extracts in Experimental Pain Models
Abstract Background: The present study aimed to evaluate the potential synergy between pharmaceutical formulations containing Bixa orellana L. (granulated—CHR OR…
Protective Action of Cannabidiol on Tiamulin Toxicity in Humans—In Vitro Study
Abstract The growing awareness and need to protect public health, including food safety, require a thorough study of the mechanism…
Quantification and time course of subjective psychotropic and somatic effects of tetrahydrocannabinol – a prospective, single-blind, placebo-controlled exploratory trial in healthy volunteers
Abstract Background: Cannabis is increasingly used and debates about the legalisation of the recreational use of cannabis are ongoing. In…
Knockdown of HGH1 in breast cancer cell lines can inhibit the viability, invasion and migration of tumor cells
Abstract Background: Research on the function of HGH1 in breast cancer remains lacking. Methods: TCGAand GEO (GSE45827) datasets investigated discrepancies…
A pan-cancer analysis of the oncogenic role of N-acetyltransferase 8 like in human cancer
Abstract Background: N-Acetyltransferase 8 Like (NAT8L) inhibits natural killer (NK)/T-cell cytotoxicity by impairing the formation of the immunological synapse via…