Characterization of the Cannabis sativa glandular trichome epigenome
Abstract Background: The relationship between epigenomics and plant specialised metabolism remains largely unexplored despite the fundamental importance of epigenomics in…
Research Article
Deciphering gene expression patterns using large-scale transcriptomic data and its applications
Abstract Gene expression varies stochastically across genders, racial groups, and health statuses. Deciphering these patterns is crucial for identifying informative…
Exploring Cannabidiol (CBD) and Cannabigerol (CBG) Safety Profile and Skincare Potential
Abstract Cannabinoids have long been known for their bioactive properties, with their topical application as anti-inflammatory compounds being at the…
Exploring the combustion, emission and performance of n-Butanol with Deccan hemp oil methyl ester on dual fuel diesel engine
Abstract This experiment investigated the feasibility of using n-butanol with Deccan hemp oil methyl ester derived from Hibiscus cannabinus. Deccan…
Antiepileptic activity and potential mechanism of full-spectrum hemp extract
Abstract Epilepsy is the fourth most common neuropsychiatric disorder. Although the approval of Epidiolex has ignited hope for patients, there…
Cannabidiol inhibits transient receptor potential canonical 4 and modulates excitability of pyramidal neurons in mPFC
Abstract Cannabidiol (CBD), a non-psychoactive compound derived from the cannabis plant, has been extensively studied for its potential therapeutic effects…
Proteomic analysis of the combined effects of cannabigerol and 3-O-ethyl ascorbic acid on kinase-dependent signalling in UVB-irradiated human keratinocytes
Abstract Oxidative stress induced by medium-wavelength ultraviolet radiation (UVB) is one of the most dangerous environmental stressors for the skin.…
Preferences for Starting Daily, On-Demand, and Long-Acting Injectable HIV Preexposure Prophylaxis Among Men Who Have Sex With Men in the United States (2021-2022): Nationwide Online Cross-Sectional Study
Abstract Background: Long-acting (LA) injectable preexposure prophylaxis (PrEP) and on-demand PrEP may improve overall PrEP uptake among men who have…
The Correlation of Bile Duct Dilatation in Postmortem Computed Tomography of Lethal Intoxication Cases for Different Drug Types—A Retrospective Study
Abstract Purpose: To assess (I) whether, in autopsy-proven lethal intoxications with opiates/opioids, a dilatation of the common bile duct (CBD)…
That men should put an enemy in their mouths to steal away their brains: Reconsidering the origins of model psychosis
Abstract The promises of the Prozac century have fallen short; the number of novel, therapeutically significant medications successfully completing development…