Research Article

April 29, 2025

Predicting Relapse of Depressive Episodes During Maintenance Treatment: The Canadian Biomarker Integration Network in Depression (CAN-BIND) Wellness Monitoring in Major Depressive Disorder Study: Prédire la rechute d’épisodes dépressifs pendant le traitement d’entretien : Une étude de suivi du bien-être dans les troubles dépressifs majeurs du Réseau canadien d’intégration des biomarqueurs pour la dépression (CAN-BIND)

Abstract Background: Relapse rates in major depressive disorder (MDD) remain high even after treatment to remission. Identifying predictors of relapse…

April 29, 2025

Addiction profile is associated with suicidal behavior and repetition of non-suicidal self injury: a latent profile analysis study in a schooled adolescents

Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00787-025-02712-x. Article type: Research Article Keywords: Addictive behavior, Suicide…

April 28, 2025

HNF4α-Mediated LINC02560 Promotes Papillary Thyroid Carcinoma Progression by Targeting the miR-505-5p/PDE4C Axis

Abstract Papillary thyroid carcinoma (PTC) is the most common subtype of thyroid malignancy, and its progression is closely associated with…

April 28, 2025

Effects of legal access versus illegal market cannabis on use and mental health: A randomized controlled trial

Abstract Aims: We measured the effects of public health‐oriented cannabis access compared with the illegal market on cannabis use and…

April 28, 2025

Re-do laparoscopic common bile duct exploration for recurrent common bile duct stones: a single-center retrospective cohort study

Abstract Purpose: Common bile duct (CBD) stone recurrence after laparoscopic CBD exploration (LCBDE) is relatively common. No studies have been…

April 28, 2025

A preliminary randomized trial of the safety, tolerability, and clinical effects of hemp-derived cannabidiol in alcohol use disorder

Abstract Introduction: Cannabidiol (CBD) has recently gained attention for its potential therapeutic effects in substance use disorders, including Alcohol Use…

April 28, 2025

Beyond Cannabidiol: The Contribution of Cannabis sativa Phytocomplex to Skin Anti-Inflammatory Activity in Human Skin Keratinocytes

Abstract Background: Cannabis sativa L. (C. sativa) has a long history of medicinal use. Its inflorescences contain bioactive compounds like…

April 28, 2025

Cannabidiol and nano-selenium mediate intestinal barrier function by affecting mucosal microstructures, and gut-associated immunological and oxidative stress response in the gut of chickens infected with C. perfringens

Abstract Nutritional additives with biological activity, such as cannabidiol (CBD) and nano-selenium (nano-Se), are viable to prevent bacterial diseases such…

April 28, 2025

Staphylococcus aureus AgrA Modulators From South African Antimicrobial Plants

Abstract South African plants are an underutilized metabolite source for novel antimicrobials targeting key quorum sensing (QS) systems like the…

April 28, 2025

Biodegradation of Juglone by Xanthomonas arboricola pv. juglandis, the Causal Agent of Walnut (Juglans regia L.) Bacterial Blight

Abstract Xanthomonas arboricola pv. juglandis is the causal agent of walnut blight, a disease affecting Juglans regia L. cultivations by…