Characterization and Variability Analysis of Volatile Metabolites From Acer saccharum Leaves From Québec Region
Abstract Volatile secondary metabolites in plants can serve as valuable biomarkers for the plant’s health, stress response, and pest or…
Research Article
Probing the Inhibitory Potential of Halogenated Symmetrical Formamidine Against MAO‐A and MAO‐B: Structural Elucidation, Molecular Dynamic Simulation and DFT Computational Studies
Abstract A halogenated symmetrical formamidine, N,N′‐bis(3‐chloro‐4‐fluorophenyl)formamidine (FCF) was synthesized by the condensation reaction between triethyl orthoformate and 3‐chloro‐4‐fluoroaniline in 1:2…
Developmental and Temperature-Driven Variations in Metabolic Profile and Antioxidant Capacity of Broccoli (Brassica oleracea var. cymosa)
Abstract This study investigates the impact of high temperature (HT) on the metabolic profile, oxidative-stress parameters, and antioxidant capacity of…
The joint role of the immune microenvironment and N7-methylguanosine for prognosis prediction and targeted therapy in acute myeloid leukemia
Abstract Background: The tumor immune microenvironment (TIME) and N7-methylguanosine (m7G) modification play crucial roles in the progression of acute myeloid…
Cannabis Legalization and Opioid Use Disorder in Veterans Health Administration Patients
Abstract Question: Were medical cannabis laws (MCLs) or recreational cannabis laws (RCLs) associated with opioid use disorder (OUD) in Veterans…
Comprehensive analysis of SELPLG as a potential immunotherapy target and prognostic biomarker in oncology
Abstract Background: SELPLG, which encodes P-selectin glycoprotein ligand-1, has emerged as a potential oncological target. A comprehensive understanding of its…
ARHGAP36 serves as a diagnostic and therapeutic marker that mediates immune escape and promotes thyroid cancer metastasis
Abstract Thyroid cancer (THCA) is a prevalent malignancy of the head and neck region, yet the mechanisms underlying its tumorigenesis…
Protocol for EpiCom: A phase 3b/4 study of behavioral outcomes following adjunctive cannabidiol for the management of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND)
Abstract Tuberous sclerosis complex (TSC)-associated neuropsychiatric disorders (TAND) affect ≈90% of individuals with TSC and significantly reduce their quality of…
Concentration-dependent effect of delta-9-tetrahydrocannabinol on epigenetic DNA modifiers in human peripheral blood mononuclear cells
Abstract Cannabis is among the most used illicit substances in the world, and approximately 10% of regular cannabis users are…
‘In the weeds’: navigating the complex concerns, challenges and choices associated with medicinal cannabis consumption for endometriosis
Abstract Abstract: People with endometriosis report consuming cannabis to manage their symptoms. Given the range of differing legalities and access…