Species distribution of Cannabis sativa: Past, present and future
Abstract Cannabis sativa L. is an annual flowering herb of Eurasian origin that has long been associated with humans. Domesticated…
Research Article
UK Medical Cannabis Registry: An Analysis of Outcomes of Medical Cannabis Therapy for Hypermobility‐Associated Chronic Pain
Abstract Objective: The study aims to evaluate the clinical outcomes in patients with hypermobility spectrum disorder (HSD) and hypermobile Ehlers–Danlos…
The role of TRAF2 in pan-cancer revealed by integrating informatics and experimental validation
Abstract Background: Tumor necrosis factor (TNF) receptor associated factor-2 (TRAF2) is an E3 ubiquitin ligase and scaffolding protein that contribute…
Endocannabinoid system upregulates the enrichment and differentiation of human iPSC- derived spermatogonial stem cells via CB2R agonism
Abstract Background: Male factor infertility (MFI) is responsible for 50% of infertility cases and in 15% of the cases sperm…
Bottom Cooling During Culture Initiation Increases Survival and Reduces Hyperhydricity in Micropropagated Cannabis Plants
Abstract Hyperhydricity is characterized by morphological abnormalities and reduced plant vigour. This study investigated the use of a bottom cooling…
Preparation and characterization of a certified reference material of toxic elements in cannabis leaves
Abstract Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s00216-025-05809-z. Article type: Research Article Keywords: Cannabis,…
The major phytocannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), affect the function of CatSper calcium channels in human sperm
Abstract STUDY QUESTION: Do the main psychoactive phytocannabinoid delta-9-tetrahydrocannabinol (THC) and its non-psychoactive analog cannabidiol (CBD) affect human sperm function?…
Risk Factors for Narcotic Use in Street Children: A Cross-Sectional Analysis From a Low-Middle-Income Country
Abstract Worldwide, indulgence in high-risk behaviors such as substance abuse is on the rise in street children. Though substance abuse…
Structure modification of luteolin and the influence of its derivatives on biological activities
Abstract Introduction: This research aims to synthesize luteolin derivatives from hemp seeds by means of chemical synthesis, improve the synthesis…
Anti-Infective Screening of Selected Nine Cannabinoids Against Clostridium perfringens and Influenza A (H5N1) Neuraminidases, and SARS-CoV-2 Main Protease and Spike Protein Interactions
Abstract Recently, cannabinoids have gained scientific interest as a promising anti-infective natural product class, as reported in several studies. However,…