Patterns of medicinal cannabis prescriptions in diverse patient populations: a retrospective analysis
Abstract Introduction: The use of medicinal cannabis is increasing worldwide and has applications in managing a wide range of conditions,…
Research Article
Retrospective Multicenter Chart Review Study of Adjunctive Cannabidiol for Seizures Associated with Lennox–Gastaut Syndrome, Dravet Syndrome and Tuberous Sclerosis Complex
Abstract Introduction: Effectiveness and tolerability of plant-derived highly purified cannabidiol (CBD) in patients with Lennox–Gastaut syndrome (LGS), Dravet syndrome (DS),…
Medicinal and combined medicinal/recreational cannabis use in California following the passage of Proposition 64
Abstract Background: Proposition 64, the Adult Use of Marijuana Act of 2016, reshaped cannabis use in California. This study explores…
Knowledge and attitudes toward recreational cannabis legalization among California residents: a population-matched questionnaire about Proposition 64
Abstract Background: Implemented in 2018, Proposition 64: The Adult Use of Marijuana Act (Prop 64; passed in 2016) legalized adult…
Observatório AlenRiscos – Prevention of the consumption of psychoactive substances among adolescents 3rd cycle
Abstract Objectives: to assess the prevalence and factors associated with psychoactive substance consumption among 7th and 9th grade students. Methods:…
Hexahydrocannabinol: pharmacokinetics, systemic toxicity, and acute behavioral effects in Wistar rats
Abstract Background: Hexahydrocannabinol (HHC) is a new psychoactive substance known for its mind-altering effects and temporary legal status. It is…
The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity
Abstract Impairment of neuronal plasticity is involved in a spectrum of neurological disorders such as epilepsy, yet its regulatory mechanisms…
Molecular determinants of 2-aminoethoxydiphenyl borate sensitivity of transient receptor potential vanilloid 2-unexpected differences between 2 rodent orthologs
Abstract Transient receptor potential vanilloid 2 (TRPV2) is relevant for diseases like cancer, cardiac dysfunction, and infection, warranting drug development…
Integrated platform for structural and functional analysis of terpene synthases of Cannabis sativa
Abstract Terpenoids are the largest and most diverse family of natural products. Volatile terpenes from Cannabis sativa are crucial in…
Cannabidiol mitigates alcohol dependence and withdrawal with neuroprotective effects in the basolateral amygdala and striatum
Abstract Alcohol use disorder (AUD) remains a pervasive public health issue with limited effective treatments. Cannabidiol (CBD), a non-psychotropic constituent…