In silico pan-cancer analysis of VRAC subunits and their prognostic roles in human cancers
Abstract The study focuses on the VRAC channel and its significant roles in cancer development. It addresses a research gap…
Research Article
Structural Variations of Broccoli Polyphenolics and Their Antioxidant Capacity as a Function of Growing Temperature
Abstract Polyphenolics in plants exist in free, soluble-bound, and insoluble-bound structural forms. The concentration of these structural forms depends on…
Biosynthesis of novel cannabigerolic acid derivatives by engineering the substrate specificity of aromatic prenyltransferase
Abstract Introduction: Cannabinoids possess significant therapeutic potential, but their natural chemical diversity derived from plant biosynthesis is limited. Efficient biotransformation…
Geographical and climatic contributions to melioidosis hotspot formation in Southern Taiwan
Abstract Melioidosis outbreaks in Taiwan frequently coincided with severe typhoons. Over a 20-year period, 782 cases of melioidosis were reported,…
Optimal nitrogen rates and clonal effects on cannabinoid yields of medicinal cannabis
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-96761-6. Article type: Research Article Keywords: THC, CBD, Fertigation,…
Cohort-based pan-cancer analysis and experimental studies reveal ISG15 gene as a novel biomarker for prognosis and immunotherapy efficacy prediction
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00262-025-04026-y. Article type: Research Article Keywords: Interferon-stimulated gene ISG15,…
Comprehensive Analysis of GPSM2: From Pan‐Cancer Analysis to Experimental Validation
Abstract G‐protein signalling modulator 2 (GPSM2) plays an important role in maintaining cell polarisation and regulating the cell cycle; however,…
Routes of Marijuana Use — Behavioral Risk Factor Surveillance System, 22 U.S. States and Two Territories, 2022
Authors: Zerleen S. Quader, Douglas R. Roehler, Alana M. Vivolo-Kantor, Jean Y. Ko License: https://creativecommons.org/publicdomain/zero/1.0/ All material in the MMWR…
Synthesis, Characterization, and Biological Effects of Chloro-Cathinones: Toxicity and Potential Neurological Impact
Abstract Cathinones, a class of synthetic new psychoactive substances (NPSs), continue to emerge and pose public threats. Government control efforts…
Targeting bladder cancer: Potent anti-cancer effects of cannabichromene and delta-9-tetrahydrocannabinol-rich Cannabis sativa strains
Abstract Objective: This study aimed to explore the anticancer potential of Cannabis sativa (C. sativa) strains, specifically PARIS, Dairy Queen…