The role of recurrent somatic mutations that alter conserved m6A motifs in human cancer
Abstract N6-methyladenosine (m6A) is the most abundant internal RNA modification in eukaryotes and plays a key role in cellular growth…
Research Article
ADCYAP1 as a pan-solid cancer biomarker: predictor of immunotherapy efficacy in bladder cancer and prognostic potential across solid tumors
Abstract Background: ADCYAP1 has been identified with potential effects ranging from tumor growth activation to inhibition. However, it remains unknown…
Pan-cancer analysis and validation show GTF2E2’s diagnostic, prognostic, and immunological roles in regulating ferroptosis in endometrial cancer
Abstract Background: Transcription initiation factor IIE subunit beta (GTF2E2) is a crucial component of the RNA polymerase II transcription initiation…
Definitive urine drug testing in emergency medicine: Recreational and psychiatric drug findings
Abstract Definitive testing for recreational drugs in emergency medicine demonstrates clinical value. Presumptive immunoassay testing limits drug detection and has…
Identification and chemical structure elucidation of synthetic cannabinoids samples seized in Kuwait during 2019–2023 using GC–MS and NMR spectroscopy
Abstract Cannabinoids, a class of chemical compounds, interact with cannabinoid receptors and are categorized into endocannabinoids, phytocannabinoids, and synthetic cannabinoids…
Cannabis Use and Misuse Following Recreational Cannabis Legalization
Abstract Question: Did cannabis use or misuse change among adults in the 5 years following recreational cannabis legalization in Canada…
Hemp Concrete with Mineral Additives as a Durable and Fire-Resistant Material in Green Construction
Abstract In this work, to enhance the compressive strength and evaluate the fire resistance of hemp concrete, we incorporated mineral…
A Prospective Comparative Study of Laparoscopic Common Bile Duct Exploration and Endoscopic Retrograde Cholangiopancreatography for Managing Common Bile Duct Calculi
Abstract Introduction: Common bile duct (CBD) calculi are typically managed by either laparoscopic CBD exploration (LCBDE) or endoscopic retrograde cholangiopancreatography…
Impact of Co-Occurring Psychiatric Comorbidities and Substance Use Disorders on Outcomes in Adolescents and Young Adults with Opioid Use Disorder: A Retrospective Cohort Study
Abstract Background/Objectives: Adolescents and young adults (AYAs) with opioid use disorder (OUD) frequently have co-occurring psychiatric conditions and substance use…
Streamlining emergency nursing care post-pandemic: A lean approach for reducing wait times and improving patient and staff satisfaction in the hospital
Abstract Background: In emergency departments (EDs), long wait times and overcrowding are major challenges, worsened by the pandemic’s increased patient…