Characterization and Variability Analysis of Volatile Metabolites From Acer saccharum Leaves From Québec Region
Abstract Volatile secondary metabolites in plants can serve as valuable biomarkers for the plant’s health, stress response, and pest or…
Research Article
Probing the Inhibitory Potential of Halogenated Symmetrical Formamidine Against MAO‐A and MAO‐B: Structural Elucidation, Molecular Dynamic Simulation and DFT Computational Studies
Abstract A halogenated symmetrical formamidine, N,N′‐bis(3‐chloro‐4‐fluorophenyl)formamidine (FCF) was synthesized by the condensation reaction between triethyl orthoformate and 3‐chloro‐4‐fluoroaniline in 1:2…
Developmental and Temperature-Driven Variations in Metabolic Profile and Antioxidant Capacity of Broccoli (Brassica oleracea var. cymosa)
Abstract This study investigates the impact of high temperature (HT) on the metabolic profile, oxidative-stress parameters, and antioxidant capacity of…
The joint role of the immune microenvironment and N7-methylguanosine for prognosis prediction and targeted therapy in acute myeloid leukemia
Abstract Background: The tumor immune microenvironment (TIME) and N7-methylguanosine (m7G) modification play crucial roles in the progression of acute myeloid…
Cannabis Legalization and Opioid Use Disorder in Veterans Health Administration Patients
Abstract Question: Were medical cannabis laws (MCLs) or recreational cannabis laws (RCLs) associated with opioid use disorder (OUD) in Veterans…
Histone demethylase JMJD2D emerges as a novel prognostic biomarker and exhibits correlation with immune infiltration in lung adenocarcinoma
Abstract Background: Lysine demethylase 4D (KDM4D or JMJD2D) plays a significant role in tumorigenesis, development, and poor clinical outcomes. However,…
Effects of supplementing bile acids on the production performance, fatty acid and bile acid composition, and gut microbiota in transition dairy cows
Abstract Background: During the transition period, cows are prone to negative energy balance, which can lead to a decline in…
Comprehensive analysis of SELPLG as a potential immunotherapy target and prognostic biomarker in oncology
Abstract Background: SELPLG, which encodes P-selectin glycoprotein ligand-1, has emerged as a potential oncological target. A comprehensive understanding of its…
ARHGAP36 serves as a diagnostic and therapeutic marker that mediates immune escape and promotes thyroid cancer metastasis
Abstract Thyroid cancer (THCA) is a prevalent malignancy of the head and neck region, yet the mechanisms underlying its tumorigenesis…
Protocol for EpiCom: A phase 3b/4 study of behavioral outcomes following adjunctive cannabidiol for the management of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND)
Abstract Tuberous sclerosis complex (TSC)-associated neuropsychiatric disorders (TAND) affect ≈90% of individuals with TSC and significantly reduce their quality of…