A male mouse model of WIN 55,212–2 self-administration to study cannabinoid addiction
Abstract We have established for the first time a mouse model of cannabinoid addiction using WIN 55,212–2 intravenous self-administration (0.0125…
Methods Article
Effects of cannabis regulation in Switzerland: Study protocol of a randomized controlled trial
Abstract Background: Cannabis is the most widely used illicit substance. Various countries have legalized cannabis for recreational use. Evidence on…
Rough-set based learning: Assessing patterns and predictability of anxiety, depression, and sleep scores associated with the use of cannabinoid-based medicine during COVID-19
Abstract Recently, research is emerging highlighting the potential of cannabinoids’ beneficial effects related to anxiety, mood, and sleep disorders as…
A protocol for rapid generation cycling (speed breeding) of hemp (Cannabis sativa) for research and agriculture
Abstract Hemp (Cannabis sativa) is a highly versatile crop with a multitude of applications, from textiles, biofuel and building material…
The Pharmacogenetics of Cannabis in the Treatment of Chronic Pain
Abstract Background: The increase in the medical use of cannabis has revealed a number of beneficial effects, a variety of…
The effects of oral and vaporized cannabis alone, and in combination with alcohol, on driving performance using the STISIM driving simulator: A two-part, double-blind, double-dummy, placebo-controlled, randomized crossover clinical laboratory protocol
Abstract The legalization of cannabis for medicinal and non-medicinal purposes, and the corresponding increase in diversity of cannabis products, has…
The Effect of Cannabis-Based Medicine on Neuropathic Pain and Spasticity in Patients with Multiple Sclerosis and Spinal Cord Injury: Study Protocol of a National Multicenter Double-Blinded, Placebo-Controlled Trial
Abstract Disease or acquired damage to the central nervous system frequently causes disabling spasticity and central neuropathic pain (NP), both…
Human Laboratory Models of Cannabis Use: Applications for Clinical and Translational Psychiatry Research
Abstract Cannabis is increasingly used by individuals with mental health diagnoses and often purported to treat anxiety and various other…
The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols in the Treatment of Adults With Chronic Tic Disorders
Abstract Background: Gilles de la Tourette syndrome (TS) is a chronic neuropsychiatric disorder characterized by motor and vocal tics. First-line…
Validation of a Bioanalytical Method for the Determination of Synthetic and Natural Cannabinoids (New Psychoactive Substances) in Oral Fluid Samples by Means of HPLC-MS/MS
Abstract New psychoactive substances (NPS) represent an important focus nowadays and are continually produced with minimal structural modifications in order…