Proof of concept for high-dose Cannabidiol pretreatment to antagonize opioid induced persistent apnea in mice
Abstract Background: Opioid related fatalities remain a public health crisis in the US. Currently, the only way to restore breathing…
Brief Report
Priming Canine Adipose Tissue-Derived Mesenchymal Stem Cells with CBD-Rich Cannabis Extract Modulates Neurotrophic Factors Expression Profile
Abstract Mesenchymal stem cells (MSCs) are used in veterinary medicine for their regenerative, immunomodulatory, and anti-inflammatory properties. Compounds from cannabis,…
Availability and affordability of cannabinoids for epilepsy treatment across different geographic settings—A survey from the ILAE Plant‐Based Therapy Task Force
Abstract Pharmacoresistant seizures remain a major challenge for the global epilepsy community. Hence, approval of highly purified pharmaceutical grade cannabidiol…
Kinin B1 receptor mediates acute cardiovascular and neural responses following cannabinoid receptor 1 activation in conscious male mice
Abstract The cannabinoid receptor 1 (CB1R) regulates cardiovascular functions and is activated by agonists such as WIN55,212‐2. While CB1R activation…
Recruiting marijuana-exposed maternal-infant dyads for longitudinal study: a feasibility assessment
Abstract Introduction: In-utero marijuana exposures are correlated with adverse neurodevelopmental outcomes in exposed neonates. As rates of marijuana use in…
Buprenorphine and cannabidiol co-administration reduces survival in a mouse model of orthopedic trauma
Abstract Introduction: Analgesic selection following orthopedic trauma presents unique challenges due to potential drug interactions and physiological stress. The impact…
Eight complete and four draft genome sequences of nonpathogenic Avibacterium paragallinarum isolates from naive, healthy layer chickens in the USA
Abstract Avibacterium paragallinarum is a primary bacterial pathogen causing infectious coryza (IC), a respiratory disease of chickens. However, nonpathogenic Avibacterium…
For those with schizophrenia, does cannabidiol make cannabis use safer?
Keywords: Schizophrenia, Drug development Authors: Anya K. Bershad ⚬ Affiliations: https://ror.org/046rm7j60grid.19006.3e0000 0000 9632 6718Department of Psychiatry and Biobehavioral Sciences, Jane…
A simple and reliable PCR-based method to differentiate between XX and XY sex genotypes in Cannabis sativa
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00425-025-04804-z. Article type: Brief Report Keywords: Cannabis sativa, CAPS,…
High acceptance and reported efficacy of cannabis for pain management in patients with rheumatic diseases in Germany: a postlegalisation survey
Abstract Objectives: Cannabis legalisation in North America has led to increased use of medical cannabis (MC) among patients with inflammatory…