Immunity in Gilles de la Tourette-Syndrome: Results From a Cerebrospinal Fluid Study
Abstract Background: Several lines of evidence support the hypothesis of an autoimmune origin of Gilles de la Tourette-Syndrome (GTS). Accordingly,…
Brief Report
Dosage Related Efficacy and Tolerability of Cannabidiol in Children With Treatment-Resistant Epileptic Encephalopathy: Preliminary Results of the CARE-E Study
Abstract Purpose: There is uncertainty regarding the appropriate dose of Cannabidiol (CBD) for childhood epilepsy. We present the preliminary data…
The dimerization of Δ9-tetrahydrocannabinolic acid A (THCA-A)
Abstract The renewed interest in dimeric salicylates as broad-spectrum anti-inflammatory and anti-diabetic agents provided a rationale to investigate the dimerization…
Association between medical cannabis laws and opioid overdose mortality has reversed over time
Abstract Medical cannabis has been touted as a solution to the US opioid overdose crisis since Bachhuber et al. [M.…
Antitumor Cannabinoid Chemotypes: Structural Insights
Abstract Cannabis has long been known to limit or prevent nausea and vomiting, lack of appetite, and pain. For this…
Gastric Parietal Cell and Intestinal Goblet Cell Secretion: a Novel Cell-Mediated In Vivo Metal Nanoparticle Metabolic Pathway Enhanced with Diarrhea Via Chinese Herbs
Abstract Electronic supplementary material: The online version of this article (10.1186/s11671-019-2908-z) contains supplementary material, which is available to authorized users.…
Exploiting the Multifaceted Effects of Cannabinoids on Mood to Boost Their Therapeutic Use Against Anxiety and Depression
Abstract The endocannabinoid system (ECS) has been recently recognized as a prominent promoter of the emotional homeostasis, mediating the effects…
Cannabis Legalization in Canada: Reflections on Public Health and the Governance of Legal Psychoactive Substances
Abstract The Canadian government is “taking a public health approach to legalizing, strictly regulating and restricting access to cannabis.” There…
Second-Hand Exposure of Staff Administering Vaporised Cannabinoid Products to Patients in a Hospital Setting
Abstract Background: In many health settings, administration of medicinal cannabis poses significant implementation barriers including drug storage and safety for…
Cannabinoid type 1 receptor-containing axons innervate NPY/AgRP neurons in the mouse arcuate nucleus
Abstract Objectives: Phytocannabinoids, such as THC and endocannabinoids, are well known to promote feeding behavior and to control energy metabolism…