Cancer cachexia: molecular basis and therapeutic advances
Abstract The dynamic interplay between neoplastic cells and the host has been increasingly recognized as important players in the pathogenesis…
Tumour immunology
Multidimensional pan cancer analysis of the sodium induced cell death gene TRPM4
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-15082-w. Article type: Research Article Keywords: TRPM4, Sodium-induced cell…
Pan-cancer analysis reveals ASCC family promotes the cancer progression of lung adenocarcinoma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-03946-0. Article type: Research Article Keywords: ASCC1/2/3, ASC-1 complex,…
Pan-cancer analysis of oncogenic role of MAGOH and experiment validation in hepatocellular carcinoma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-08678-9. Article type: Research Article Keywords: MAGOH (Mago-nashi homolog),…
Prediction and analysis of tumor infiltrating lymphocytes across 28 cancers by TILScout using deep learning
Abstract The density of tumor-infiltrating lymphocytes (TILs) serves as a valuable indicator for predicting anti-tumor responses, but its broad impact…
Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-85444-x. Article type: Research Article Keywords: NTN1, Pan-cancer, Biomarker,…
Integrative pan-cancer analysis and experiment validation identified GLS as a biomarker in tumor progression, prognosis, immune microenvironment, and immunotherapy
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-84916-w. Article type: Research Article Keywords: GLS, Pan-cancer analysis,…
Multi-omics analysis identifies BCAT2 as a potential pan-cancer biomarker for tumor progression and immune microenvironment modulation
Abstract Branched-chain amino acid transaminase 2 (BCAT2) encodes a crucial protein involved in the initial catalysis of branched-chain amino acid…
Pan-cancer analysis of the prognostic and immunological roles of SHP-1/ptpn6
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-74037-9. Article type: Research Article Keywords: Pan-cancer, Immune infiltration,…
Pan-cancer analysis of the immunological and oncogenic roles of ATAD2 with verification in papillary thyroid carcinoma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-73274-2. Article type: Research Article Keywords: ATAD2, Pan-cancer, Papillary…