HLF is a promising prognostic, immunological, and therapeutic biomarker in human tumors
Abstract Despite past research linking HLF mutations to cancer development, no pan-cancer analyses of HLF have been published. As a…
tumor-infiltrating immune cells
Comprehensive analysis of transcriptome data and experimental identification show that solute carrier 35 member A2 (SLC35A2) is a prognostic marker of colorectal cancer
Abstract Background: Colorectal cancer (CRC) is a solid tumor with high morbidity and mortality rates. Accumulating evidence shows that the…
A Comprehensive Pan-Cancer Analysis of the Tumorigenic Role of Matrix Metallopeptidase 7 (MMP7) Across Human Cancers
Abstract Growing evidence has shown the oncogenic function of matrix metallopeptidase 7 (MMP7) in various tumors. However, no systemic pan-cancer…
KCNN4 is a Potential Biomarker for Predicting Cancer Prognosis and an Essential Molecule that Remodels Various Components in the Tumor Microenvironment: A Pan-Cancer Study
Abstract Objectives: Potassium Calcium-Activated Channel Subfamily N Member 4 (KCNN4) is a member of the KCNN family. Studies have revealed…
Comprehensive analysis of ZFPM2-AS1 prognostic value, immune microenvironment, drug sensitivity, and co-expression network: from gastric adenocarcinoma to pan-cancers
Abstract Background: ZFPM2-AS1, as an oncogenic lncRNA, plays an essential role in the progression of several tumors. However, the prognostic…
Association of a Novel Prognosis Model with Tumor Mutation Burden and Tumor-Infiltrating Immune Cells in Thyroid Carcinoma
Abstract Although immunotherapy has recently demonstrated a substantial promise in treating advanced thyroid carcinoma (THCA), it is not appropriate for…
The prognostic value of plasma complement factor B (CFB) in thyroid carcinoma
Abstract Stromal and immune cells are major components of tumor microenvironment (TME) and affect the growth and development of thyroid…
Comprehensive Analysis of the Potential Immune-Related Biomarker Transporter Associated With Antigen Processing 1 That Inhibits Metastasis and Invasion of Ovarian Cancer Cells
Abstract Transporter associated with antigen processing 1 (TAP1) is a protein related immune regulation and plays a role in several…
Landscape of the oncogenic role of fatty acid synthase in human tumors
Abstract Background: Identifying a unique and common regulatory pathway that drives tumorigenesis in cancers is crucial to foster the development…
Comprehensive Transcriptomic Analysis Reveals the Role of the Immune Checkpoint HLA-G Molecule in Cancers
Abstract Human leukocyte antigen G (HLA-G) is known as a novel immune checkpoint molecule in cancer; thus, HLA-G and its…