RXRG as a Novel Biomarker and its Correlation With Immune Infiltration in Thyroid Carcinoma
Abstract Background/Aim: Thyroid carcinoma (THCA) is the most prevalent type of endocrine cancer. Retinoid X Receptor Gamma (RXRG) encodes a…
tumor immune infiltration
Comprehensive pan-cancer analysis reveals ENC1 as a promising prognostic biomarker for tumor microenvironment and therapeutic responses
Abstract Accumulating research showed that ENC1 plays a critical role in maintaining the physiological functions. However, little is known about…
PIK3CD correlates with prognosis, epithelial–mesenchymal transition and tumor immune infiltration in breast carcinoma
Abstract Background: Breast carcinoma (BRCA) is one of the most common, fatal, and aggressive cancers, with increasing morbidity that has…
Pan-cancer analysis of aldolase B gene as a novel prognostic biomarker for human cancers
Abstract Aldolase B (ALDOB) gene is essential for the process of glycolysis and differentially expressed in cancers. The aims of…
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12902-022-01203-3. Article type: Research Article Keywords: Thyroid carcinoma, TMPRSS4,…
Pan-cancer analysis of UBE2T with a focus on prognostic and immunological roles in lung adenocarcinoma
Abstract Background: Ubiquitin-conjugating enzyme E2 T (UBE2T) is a potential oncogene. However, Pan-cancer analyses of the functional, prognostic and predictive…
SQLE, A Key Enzyme in Cholesterol Metabolism, Correlates With Tumor Immune Infiltration and Immunotherapy Outcome of Pancreatic Adenocarcinoma
Abstract Background: Pancreatic adenocarcinoma (PAAD) is a treatment-refractory cancer with poor prognosis. Accumulating evidence suggests that squalene epoxidase (SQLE) plays…
COMMD2 Upregulation Mediated by an ncRNA Axis Correlates With an Unfavorable Prognosis and Tumor Immune Infiltration in Liver Hepatocellular Carcinoma
Abstract Liver hepatocellular carcinoma (LIHC) seriously endangers the health and quality of life of individuals worldwide. Increasing evidence has underscored…
Pan-cancer analysis of necroptosis-related gene signature for the identification of prognosis and immune significance
Abstract Background: Necroptosis is a novel programmed cell death mode independent on caspase. A number of studies have revealed that…
LPAR2 correlated with different prognosis and immune cell infiltration in head and neck squamous cell carcinoma and kidney renal clear cell carcinoma
Abstract Background: Lysophosphatidic acid (LPA) and its receptors play a key role in regulating cancer progression. Upregulation of LPA receptor…