TRPV4

August 7, 2025

TRP channels in hepatocellular carcinoma: integrative Mendelian randomization and multi-omics analyses highlight MCOLN3/TRPV4 as candidate dual-effect biomarkers

Abstract Background: The causal relationship between Transient receptor potential (TRP) and hepatocellular carcinoma (HCC) remains unclear. Our study aimed to…

June 28, 2021

TRPV4 is a Prognostic Biomarker that Correlates with the Immunosuppressive Microenvironment and Chemoresistance of Anti-Cancer Drugs

Abstract Background: Transient receptor potential cation channel subfamily V member 4 (TRPV4) has been reported to regulate tumor progression in…

December 9, 2020

An Analysis of the Putative CBD Binding Site in the Ionotropic Cannabinoid Receptors

Abstract Cannabinoids have been long studied for their therapeutic properties, particularly for their use in the treatment of pain. As…

May 14, 2020

Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

Abstract Swelling of the brain or spinal cord (CNS edema) affects millions of people every year. All potential pharmacological interventions…