TRPV1 receptors

December 14, 2020

CannabinEYEds: The Endocannabinoid System as a Regulator of the Ocular Surface Nociception, Inflammatory Response, Neovascularization and Wound Healing

Abstract The endocannabinoid system (ECS) is a complex regulatory system, highly conserved among vertebrates. It has been widely described in…

June 5, 2020

Anticonvulsive Properties of Cannabidiol in a Model of Generalized Seizure Are Transient Receptor Potential Vanilloid 1 Dependent

Abstract Introduction: Highly purified cannabidiol (CBD) (approved as Epidiolex® in the United States) has demonstrated efficacy with an acceptable safety…

May 22, 2019

Cannabidiol Affects the Bezold-Jarisch Reflex via TRPV1 and 5-HT3 Receptors and Has Peripheral Sympathomimetic Effects in Spontaneously Hypertensive and Normotensive Rats

Abstract Cannabidiol (CBD) is a nonpsychotropic constituent of Cannabis sativa L. It is suggested to be useful in hypertension. Under…

January 15, 2019

Cannabinoid Ligands Targeting TRP Channels

Abstract Transient receptor potential (TRP) channels are a group of membrane proteins involved in the transduction of a plethora of…

April 24, 2018

Emerging Role of (Endo)Cannabinoids in Migraine

Abstract In this mini-review, we summarize recent discoveries and present new hypotheses on the role of cannabinoids in controlling trigeminal…

August 1, 2013

A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice

Abstract Objective: The G protein-coupled receptor 55 (GPR55) is a novel cannabinoid (CB) receptor, whose role in the gastrointestinal (GI)…