Abstract Nicandrin B (Nic B), a withanolide isolated from Datura ferox leaves, was investigated for its antinociceptive and anti‐inflammatory effects…
Abstract Background: Calcitonin gene-related peptide (CGRP) release from trigeminal structures is central to migraine pathophysiology. This study employed an ex…
Abstract Affinin (spilanthol) is the main bioactive alkylamide present in Heliopsis longipes roots, exerting antinociceptive and anti-inflammatory effects that involve…
Abstract The gustatory system is responsible for detecting and evaluating the palatability of the various chemicals present in food and…
Abstract Background: Atopic dermatitis (AD) is one of the most common cutaneous inflammatory and pruritic diseases in dogs. Considering its…
Abstract It is commonly accepted that some form of skin barrier dysfunction is present in canine atopic dermatitis (AD), one…
Abstract Background: The transient receptor potential vanilloid 1 (TRPV1) participates in thermosensation and inflammatory pain, but its immunomodulatory mechanisms remain…
Abstract We have previously shown that bilateral common carotid artery occlusion followed by reperfusion (BCCAO/R) is a model to study…
Abstract Simple Summary: The endocannabinoid system (ECS) has opened the door to novel therapeutical approaches targeting cancer, pain, anxiety, stress,…
Abstract Osteoarthritis (OA) is a degenerative joint disease manifested by movement limitations and chronic pain. Endocannabinoid system (ECS) may modulate…