tRNA-derived fragment

February 10, 2026

TRMT6/TRMT61A-mediated tRNA m1A modification enhances protein translation and activates the IRE1α–XBP1s pathway to promote anaplastic thyroid cancer progression

Abstract Background: Anaplastic thyroid cancer (ATC) is a highly aggressive malignancy with rapid progression and poor prognosis. Although N1-methyladenosine (m1A)…

October 2, 2024

Computational Analysis Suggests That AsnGTT 3′-tRNA-Derived Fragments Are Potential Biomarkers in Papillary Thyroid Carcinoma

Abstract Transfer-RNA-derived fragments (tRFs) are a novel class of small non-coding RNAs that have been implicated in oncogenesis. tRFs may…

February 1, 2021

NMR Characterization of Angiogenin Variants and tRNAAla Products Impacting Aberrant Protein Oligomerization

Abstract Protein oligomerization is key to countless physiological processes, but also to abnormal amyloid conformations implicated in over 25 mortal…