GPR34 Stabilized by Deubiquitinase USP8 Suppresses Ferroptosis of ATC
Abstract G protein-coupled receptor 34 (GPR34) is an orphan receptor within the G protein-coupled receptor (GPCR) superfamily, and its specific…
(trans)dermal patch
An open-label feasibility trial of transdermal cannabidiol for hand osteoarthritis
Abstract Hand osteoarthritis (OA) is an irreversible degenerative condition causing chronic pain and impaired functionality. Existing treatment options are often…
Tick-borne encephalitis virus capsid protein induces translational shutoff as revealed by its structural–biological analysis
Abstract Tick-borne encephalitis virus (TBEV) is the most medically relevant tick-transmitted Flavivirus in Eurasia, targeting the host central nervous system…
MiRNA Deregulation Distinguishes Anaplastic Thyroid Carcinoma (ATC) and Supports Upregulation of Oncogene Expression
Abstract Simple Summary: MicroRNAs are essential regulators of gene expression. Their deregulation is associated with a substantial reorganization of the…
Topical Administration of Cannabidiol: Influence of Vehicle-Related Aspects on Skin Permeation Process
Abstract Cannabidiol (CBD) is a non-psychoactive cannabinoid isolated from Cannabis sativa which, given its claimed beneficial properties and therapeutic potential,…