Sex differences in the disposition of cannabidiol and its metabolites in mice
Abstract Background: While cannabidiol (CBD) is widely used globally as a therapeutic agent, sex as a biological variable remains underexplored…
tissue distribution
Orally consumed cannabinoids: the effect of carrier oil on acute tissue distribution in male C57BL/6 mice
Abstract Background: Fundamental gaps in knowledge exist in understanding the tissue distribution of cannabinoids, cannabidiol (CBD) and tetrahydrocannabinol (THC), following…
Strategies to Improve Cannabidiol Bioavailability and Drug Delivery
Abstract The poor physicochemical properties of cannabidiol (CBD) hamper its clinical development. The aim of this review was to examine…
Distribution of Synthetic Cannabinoids JWH-210, RCS-4 and ∆ 9-Tetrahydrocannabinol After Intravenous Administration to Pigs
Abstract Background: Synthetic cannabinoids (SCs) have become an increasing issue in forensic toxicology. Controlled human studies evaluating pharmacokinetic data of…