Clinical implications of SLC26A7 in thyroid carcinoma: An observational study from TCGA and GEO
Abstract Thyroid carcinoma (THCA) is a common malignant endocrine tumor. Previously, we found that the expression of solute carrier family…
The Cancer Genome Atlas
The Prognostic Significance of NEDD9 Expression in Human Cancers: A Systematic Review, Meta-Analysis, and Omics Exploration
Abstract Background: Neural precursor cell expressed developmentally downregulated 9 (NEDD9) is considered an important factor in the progression of cancer,…
Actin-related protein 2/3 complex subunit 1B promotes ovarian cancer progression by regulating the AKT/PI3K/mTOR signaling pathway
Abstract Background and Objectives: Actin-related protein 2/3 complex subunit 1B (ARPC1B) is an essential subunit of the actin-related protein 2/3…
FN1, a reliable prognostic biomarker for thyroid cancer, is associated with tumor immunity and an unfavorable prognosis
Abstract Thyroid cancer (THCA) is a malignant tumor that affects the endocrine system. At present, an effective treatment for THCA…
A comprehensive pan-cancer analysis revealing the role of ITPRIPL1 as a prognostic and immunological biomarker
Abstract Inositol 1,4,5-Trisphosphate Receptor-Interacting Protein-Like 1 (ITPRIPL1), a single-pass type I membrane protein located in the membrane, functions as an…
Exploration and validation of key genes associated with early lymph node metastasis in thyroid carcinoma using weighted gene co-expression network analysis and machine learning
Abstract Background: Thyroid carcinoma (THCA), the most common endocrine neoplasm, typically exhibits an indolent behavior. However, in some instances, lymph…
Systematic analysis of the prognosis and immune infiltration of E2Fs in thyroid carcinoma
Abstract Purpose: To evaluate the diagnostic and prognostic utility of E2F transcription factors (E2Fs) in thyroid carcinoma (THCA) and their…
Comparison of the Basal Cell Carcinoma (BCC) Tumour Microenvironment to Other Solid Malignancies
Abstract Simple Summary: Basal cell carcinoma is the most common human cancer. Most BCCs are low-risk and are easily treated;…
Pan-cancer Landscape of the RUNX Protein Family Reveals their Potential as Carcinogenic Biomarkers and the Mechanisms Underlying their Action
Abstract Background: The RUNX family of transcription factors plays an important regulatory role in tumor development. Although the importance of…
Identifies microtubule-binding protein CSPP1 as a novel cancer biomarker associated with ferroptosis and tumor microenvironment
Keywords: TME, tumor microenvironment, CAF, cancer-associated fibroblasts, EMT, epithelial-mesenchymal transition, DLBC, diffuse large B-cell lymphoma, TCGA, The Cancer Genome Atlas,…