TGCT

September 17, 2022

Comprehensive analysis of tumor necrosis factor-α-inducible protein 8-like 2 (TIPE2): A potential novel pan-cancer immune checkpoint

Keywords: LAML, Acute Myeloid Leukemia, BLCA, Bladder Urothelial Carcinoma, BRCA, Breast invasive carcinoma, CESC, Cervical squamous cell carcinoma and endocervical…

June 27, 2022

Comprehensive analysis of the novel omicron receptor AXL in cancers

Keywords: COVID-19, coronavirus disease 2019, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, ACE2, angiotensin-converting enzyme 2, AXL, anexelekto, UMAP, uniform…

June 24, 2022

Identifies microtubule-binding protein CSPP1 as a novel cancer biomarker associated with ferroptosis and tumor microenvironment

Keywords: TME, tumor microenvironment, CAF, cancer-associated fibroblasts, EMT, epithelial-mesenchymal transition, DLBC, diffuse large B-cell lymphoma, TCGA, The Cancer Genome Atlas,…

June 18, 2022

Identification of SHCBP1 as a potential biomarker involving diagnosis, prognosis, and tumor immune microenvironment across multiple cancers

Keywords: AUC, area under the curve, CCLE, cancer cell line encyclopedia, HR, hazard ratio, ROC, receiver operating characteristic, SHCBP1, Shc…

January 7, 2022

Violations of proportional hazard assumption in Cox regression model of transcriptomic data in TCGA pan-cancer cohorts

Keywords: CPH, Cox proportional hazard regression, PH, proportional hazard, TCGA, The Cancer Genome Atlas, OS, overall survival, GEO, Gene Expression…

November 9, 2020

A pan-cancer analysis of HER2 index revealed transcriptional pattern for precise selection of HER2-targeted therapy

Abstract Background: The prevalence of HER2 alterations in pan-cancer indicates a broader range of application of HER2-targeted therapies; however, biomarkers…

October 21, 2020

Integrative omics analysis reveals relationships of genes with synthetic lethal interactions through a pan-cancer analysis

Keywords: ACC, adrenocortical carcinoma, BLCA, bladder urothelial carcinoma, BRCA, breast invasive carcinoma, CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma,…

May 13, 2020

Rewired functional regulatory networks among miRNA isoforms (isomiRs) from let-7 and miR-10 gene families in cancer

Keywords: ACC, adrenocortical carcinoma, BLCA, bladder urothelial carcinoma, BRCA, breast invasive carcinoma, CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma,…

March 19, 2020

PreMSIm: An R package for predicting microsatellite instability from the expression profiling of a gene panel in cancer

Keywords: Cancer, Microsatellite instability, Gene expression profiling, Machine learning, Algorithm, Classification, AUC, area under the curve, CV, cross validation, GEO,…