Cross-sectional comparison of cannabis use in adults with neuropathic versus non-neuropathic pain
Abstract Introduction: Cannabis has been decriminalized by many states and shows promise in treating both neuropathic and non-neuropathic pain through…
Tetrahydrocannabinol (THC)
Maximizing Cannabinoid and Polyphenol Extraction from Industrial Hemp (Cannabis sativa L. cv. Helena) Areal Parts: A Comparative Study of Ultrasound-Assisted and Conventional Methods at Two Harvest Stages
Abstract In this work, two extraction techniques, conventional and ultrasound-assisted extraction (UAE) techniques, were employed for the extraction of natural…
Therapeutic potential of cannabinoids in neurological conditions: a systematic review of clinical trials
Abstract Overview: Cannabinoids have gained increasing attention for their therapeutic potential in treating several neurological conditions, including neurodegenerative diseases, chronic…
Dronabinol Is Not a Game Changer in Pediatric Palliative Care: Results from a Retrospective Study
Abstract Background/Objectives: Patients with life-limiting conditions (LLCs) often suffer from restlessness, spasticity, pain, and seizures. Dronabinol (DRB) may have a…
Efficacy of cannabinoids compared to the current standard treatments on symptom relief in persons with multiple sclerosis (CANSEP trial): study protocol for a randomized clinical trial
Abstract Background: Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system. More than 90,000 Canadians…
Safety of cannabidiol products as a social issue: A case series
Abstract Background: Cannabidiol (CBD) products have increased in popularity in Japan in recent years, particularly among young people. Some CBD…
Phytocannabinoids: Exploring Pharmacological Profiles and Their Impact on Therapeutical Use
Abstract Phytocannabinoids, a diverse group of naturally occurring compounds extracted from the Cannabis plant, have attracted interest due to their…
Vogt–Koyanagi–Harada disease with a unilateral presentation in a patient with marijuana overuse: Role of multimodal imaging in suspected patients
Abstract Key Clinical Message: Harada disease could uniquely present with only unilateral symptoms, as was seen in our patient. However,…
Moon Rock Cannabis-Induced Psychosis and New-Onset Seizures in a 20-Year-Old Male
Abstract “Moon rock” cannabis is a type of new and highly potent preparation of cannabis, which is made of a…
Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol
Abstract The cannabinoids cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) undergo extensive oxidative metabolism in the liver. Although cytochromes P450 form the…