Biased data, biased AI: deep networks predict the acquisition site of TCGA images
Abstract Background: Deep learning models applied to healthcare applications including digital pathology have been increasing their scope and importance in…
TCGA
An integrative pan-cancer analysis illustrating the key role of LRP11 in cervical cancer
Abstract Methods: The original tumor data was downloaded from the Cancer Genome Atlas and genotype-tissue expression databases. The expression of…
Identification of a Novel Cuproptosis-Related Gene Signature and Integrative Analyses in Thyroid Cancer
Abstract Cuproptosis is a novel programmed cell death that depends on copper. The role and potential mechanism of cuproptosis-related genes…
GPR65 as a potential immune checkpoint regulates the immune microenvironment according to pan-cancer analysis
Abstract It has been reported that inhibition of GPR65 may be effective for the treatment of certain cancers. Nevertheless, the…
Molecular Genetic Characteristics of FANCI, a Proposed New Ovarian Cancer Predisposing Gene
Abstract FANCI was recently identified as a new candidate ovarian cancer (OC)-predisposing gene from the genetic analysis of carriers of…
HMMR potential as a diagnostic and prognostic biomarker of cancer—speculation based on a pan-cancer analysis
Abstract Background: Although the status of universal upregulation for the Hyaluronan-Mediated Motility Receptor (HMMR) in pan-cancer is still unknown, HMMR…
Comparison of the Basal Cell Carcinoma (BCC) Tumour Microenvironment to Other Solid Malignancies
Abstract Simple Summary: Basal cell carcinoma is the most common human cancer. Most BCCs are low-risk and are easily treated;…
S100A11: A Potential Carcinogen and Prognostic Marker That Correlates with the Immunosuppressive Microenvironment in Pan-Cancer
Abstract S100 calcium-binding protein A11 (S100A11) has been proved to be an oncogene of most tumors. However, its role in…
Integrative analysis deciphers the heterogeneity of cancer-associated fibroblast and implications on clinical outcomes in ovarian cancers
Keywords: scRNA-seq, Single-cell RNA-sequencing, CAFs, Cancer-associated fibroblasts, HGSOC, High-grade serous ovarian carcinoma, TCGA, The Cancer Genomics Atlas, LUAD, Lung adenocarcinoma,…
DHRS7 is an immune-related prognostic biomarker of KIRC and pan-cancer
Abstract Renal clear cell carcinoma (KIRC) is one malignancy whose development and prognosis have been associated with aberrant DHRS7 expression.…