A Pan-Cancer Analysis of CD161, a Potential New Immune Checkpoint
Abstract Background: CD161, encoded by killer cell lectin-like receptor B1 gene, is a newly reported candidate inhibitor of tumour-infiltrating T…
TCGA
FOXD1 is a prognostic biomarker and correlated with macrophages infiltration in head and neck squamous cell carcinoma
Abstract Background: Forkhead Box D1 (FOXD1) is differentially expressed in various tumors. However, its role and correlation with immune cell…
Evidence of Omics, Immune Infiltration, and Pharmacogenomic for SENP1 in the Pan-Cancer Cohort
Abstract Sentrin specific-protease 1 (SENP1) is a protein involved in deSUMOylation that is almost overexpressed in cancer. SENP1 has a…
A Reductionist Approach Using Primary and Metastatic Cell–Derived Extracellular Vesicles Reveals Hub Proteins Associated with Oral Cancer Prognosis
Abstract Oral squamous cell carcinoma (OSCC) has high mortality rates that are largely associated with lymph node metastasis. However, the…
A pan-cancer survey of cell line tumor similarity by feature-weighted molecular profiles
Abstract Patient-derived cell lines are often used in pre-clinical cancer research, but some cell lines are too different from tumors…
Pan-cancer chromatin analysis of the human vtRNA genes uncovers their association with cancer biology
Abstract Background: The vault RNAs (vtRNAs) are a class of 84-141-nt eukaryotic non-coding RNAs transcribed by RNA polymerase III, associated…
Evidence of Cooperation between Hippo Pathway and RAS Mutation in Thyroid Carcinomas
Abstract Simple Summary: RAS mutations have been reported in a wide range of thyroid cancer histological types, from benign to…
The Association between TIF1 Family Members and Cancer Stemness in Solid Tumors
Abstract Simple Summary: Stem cell-associated molecular features of solid tumors, collectively known as cancer stemness, are of great importance in…
HILPDA Is a Prognostic Biomarker and Correlates With Macrophage Infiltration in Pan-Cancer
Abstract Background: The protein hypoxia-inducible lipid droplet-associated (HILPDA) is differentially expressed in various tumors. However, its role and correlation with…
Comprehensive Analysis of the Functions and Prognostic Value of RNA-Binding Proteins in Thyroid Cancer
Abstract RNA binding proteins (RBPs) have been proved to play pivotal roles in a variety types of tumors. However, there…