Screening microbially produced Δ9-tetrahydrocannabinol using a yeast biosensor workflow
Abstract Microbial production of cannabinoids promises to provide a consistent, cheaper, and more sustainable supply of these important therapeutic molecules.…
synthetic biology
Engineering consortia by polymeric microbial swarmbots
Abstract Synthetic microbial consortia represent a new frontier for synthetic biology given that they can solve more complex problems than…
A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination
Abstract Eukaryotic cells use G-protein coupled receptors to sense diverse signals, ranging from chemical compounds to light. Here, we exploit…
The Biochemistry of Phytocannabinoids and Metabolic Engineering of Their Production in Heterologous Systems
Abstract The medicinal properties of cannabis and the its legal status in several countries and jurisdictions has spurred the massive…
Bioengineering studies and pathway modeling of the heterologous biosynthesis of tetrahydrocannabinolic acid in yeast
Abstract Heterologous biosynthesis of tetrahydrocannabinolic acid (THCA) in yeast is a biotechnological process in Natural Product Biotechnology that was recently…
Systems and Synthetic Biology Approaches to Engineer Fungi for Fine Chemical Production
Abstract Since the advent of systems and synthetic biology, many studies have sought to harness microbes as cell factories through…
A stimulus-responsive, in situ-forming, nanoparticle-laden hydrogel for ocular drug delivery
Abstract Most medications targeting optic neuropathies are administered as eye drops. However, their corneal penetration efficiencies are typically < 5%.…
Designing microorganisms for heterologous biosynthesis of cannabinoids
Abstract During the last decade, the use of medical Cannabis has expanded globally and legislation is getting more liberal in…