Somatic Mutation Accumulations in Micropropagated Cannabis Are Proportional to the Number of Subcultures
Abstract Advancements in micropropagation techniques have made it easier to produce large numbers of cannabis clones, but these methods may…
somatic mutations
Systematic integration of protein-affecting mutations, gene fusions, and copy number alterations into a comprehensive somatic mutational profile
Abstract Somatic mutations occur as random genetic changes in genes through protein-affecting mutations (PAMs), gene fusions, or copy number alterations…
Identification of Somatic Mitochondrial DNA Mutations, Heteroplasmy, and Increased Levels of Catenanes in Tumor Specimens Obtained from Three Endometrial Cancer Patients
Abstract Endometrial carcinoma (EC) is the most common type of gynecologic malignant epithelial tumor, with the death rate from this…
Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants
Abstract Background: In recent years, research on cancer predisposition germline variants has emerged as a prominent field. The identity of…
Mutational landscape of RNA-binding proteins in human cancers
Abstract RNA Binding Proteins (RBPs) are a class of post-transcriptional regulatory molecules which are increasingly documented to be dysfunctional in…