Persistent sodium currents in neurons: potential mechanisms and pharmacological blockers
Abstract Persistent sodium current (INaP) is an important activity-dependent regulator of neuronal excitability. It is involved in a variety of…
Slow inactivation
Cannabidiol Selectively Binds to the Voltage-Gated Sodium Channel Nav1.4 in Its Slow-Inactivated State and Inhibits Sodium Current
Abstract Cannabidiol (CBD), one of the cannabinoids from the cannabis plant, can relieve the myotonia resulting from sodium channelopathy, which…