siRNA

September 18, 2025

Cholesterol modified defense peptide as an EMP2-siRNA delivery system for synergistic immunogene therapy against breast cancer

Abstract Epithelial membrane protein 2 (EMP2) plays crucial roles in cell proliferation, migration, and adhesion. Despite its importance, conventional EMP2…

May 19, 2022

Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells Cultured in 3D Spheroids

Abstract Cationic dendrimers are effective carriers for the delivery of siRNA into cells; they can penetrate cell membranes and protect…

July 1, 2021

Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells

Abstract The application of siRNA in gene therapy is mainly limited because of the problems with its transport into cells.…

July 29, 2019

Knockdown of estrogen receptor β increases proliferation and affects the transcriptome of endometrial adenocarcinoma cells

Abstract Background: Estrogen receptor β (ERβ) has been repeatedly suggested to play important roles in hormone-dependent cancer like in tumors…