Nav1.8, an analgesic target for nonpsychotomimetic phytocannabinoids
Abstract Chronic pain is a major health problem worldwide; however, treatment options remain limited and often involve adverse side-effects or…
sensory neurons
Terpenes in Cannabis sativa Inhibit Capsaicin Responses in Rat DRG Neurons via Na+/K+ ATPase Activation
Abstract Terpenes in Cannabis sativa exert analgesic effects, but the mechanisms are uncertain. We examined the effects of 10 terpenes…
Voltage-gated sodium channels in diabetic sensory neuropathy: Function, modulation, and therapeutic potential
Abstract Voltage-gated sodium channels (NaV) are the main contributors to action potential generation and essential players in establishing neuronal excitability.…