CBC Complex Regulates Hyphal Growth, Sclerotial Quantity, and Pathogenicity in the Necrotrophic Fungus Botrytis cinerea
Abstract The cap-binding protein complex (CBC), comprising Cbp20 and Cbp80, is crucial for gene expression, yet its role in the…
RRM
Paip2A inhibits translation by competitively binding to the RNA recognition motifs of PABPC1 and promoting its dissociation from the poly(A) tail
Abstract Eukaryotic mRNAs possess a poly(A) tail at their 3′-end, to which poly(A)-binding protein C1 (PABPC1) binds and recruits other…
Intrinsically disordered electronegative clusters improve stability and binding specificity of RNA-binding proteins
Abstract RNA-binding proteins play crucial roles in various cellular functions and contain abundant disordered protein regions. The disordered regions in…
Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7
Abstract HnRNP A1 regulates many alternative splicing events by the recognition of splicing silencer elements. Here, we provide the solution…
Distinct binding properties of TIAR RRMs and linker region
Abstract The RNA-binding protein TIAR is an mRNA-binding protein that acts as a translational repressor, particularly important under conditions of…