Abstract Introduction: Lennox–Gastaut syndrome (LGS) is a particularly severe developmental epileptic encephalopathy (DEE) characterized by multiple types of drug-resistant, incapacitating…
Abstract Aim: We developed a living systematic review (LSR) that will continuously map the safety and reported benefit data related…
Abstract Pediatric genetic epilepsies, such as CDKL5 Deficiency Disorder (CDD), are severely debilitating, with early-onset seizures occurring more than ten…
Abstract Aim: To evaluate the comparative efficacy and safety of various doses of oral cannabidiol (CBD) in treating refractory epilepsy…
Abstract Objectives: Epilepsy poses a significant challenge in pediatric and adolescent populations, impacting not only seizures but also psychological and…
Abstract Cannabis sativa is one of the first medicinal plants used by humans. Its medical use remains controversial because it…
Abstract Background: The Compassionate Access Scheme (CAS) being delivered through the Queensland Children’s Hospital is designed to allow access to…
Abstract Cannabidiol (CBD), a lipophilic cannabinoid compound without psychoactive effects, has emerged as adjuvant of anti-epileptic drugs (AEDs) in the…
Abstract Refractory epilepsy is a chronic brain network disorder characterized by unresponsiveness to multiple (>2) anti-epileptic drugs. Cannabidiol, a non-psychotropic…
Abstract Objectives: There is an increasing interest in cannabinoid-based products for the treatment of refractory pediatric epilepsy. However, a licensed…