Cannabinoid and Orexigenic Systems Interplay as a New Focus of Research in Alzheimer’s Disease
Abstract Alzheimer’s disease (AD) remains a significant health challenge, with an increasing prevalence globally. Recent research has aimed to deepen…
receptor heteromer
The Binding Mode to Orthosteric Sites and/or Exosites Underlies the Therapeutic Potential of Drugs Targeting Cannabinoid CB2 Receptors
Abstract The classical terms agonists and antagonists for G protein coupled receptors (GPCRs) have often become misleading. Even the biased…
The Dynamic Role of Microglia and the Endocannabinoid System in Neuroinflammation
Abstract Microglia, the resident immune cells of the brain, can take on a range of pro- or anti-inflammatory phenotypes to…
The Endocannabinoid System as a Target in Cancer Diseases: Are We There Yet?
Abstract The endocannabinoid system (ECS) has been placed in the anti-cancer spotlight in the last decade. The immense data load…