Effects of cannabis regulation in Switzerland: Study protocol of a randomized controlled trial
Abstract Background: Cannabis is the most widely used illicit substance. Various countries have legalized cannabis for recreational use. Evidence on…
randomized controlled trial
Cannabis-opioid interaction in the treatment of fibromyalgia pain: an open-label, proof of concept study with randomization between treatment groups: cannabis, oxycodone or cannabis/oxycodone combination—the SPIRAL study
Abstract Background: Opioids continue to be widely prescribed for chronic noncancer pain, despite the awareness that opioids provide only short-time…
Xanthohumol microbiome and signature in adults with Crohn’s disease (the XMaS trial): a protocol for a phase II triple-masked, placebo-controlled clinical trial
Abstract Background: Xanthohumol (XN), a bioactive flavonoid from Humulus lupulus with anti-inflammatory properties, has potential benefits for patients with Crohn’s…
Prazosin for the management of behavioural and psychological symptoms of dementia
Abstract Prazosin, a centrally acting α1 adrenoceptor antagonist, has been included in two published algorithms amongst the list of medications…
Cannabinoids in the Treatment of Cannabis Use Disorder: Systematic Review of Randomized Controlled Trials
Abstract Background: The prevalence of cannabis use and cannabis use disorders (CUD) has significantly increased over time. However, there are…
CANreduce-SP—adding psychological support to web-based adherence-focused guided self-help for cannabis users: study protocol for a three-arm randomized control trial
Abstract Background: Cannabis is the most-frequently used illicit drug in Europe. Over the last few years in Spain, treatment demand…
Comparing a mindfulness- and CBT-based guided self-help Internet- and mobile-based intervention against a waiting list control condition as treatment for adults with frequent cannabis use: a randomized controlled trial of CANreduce 3.0
Abstract Background: Though Internet- and mobile-based interventions (IMIs) and mindfulness-based interventions (generally delivered in-situ) appear effective for people with substance…
Cannabinoids for the Treatment of Dermatologic Conditions
Abstract In recent years, cannabinoid (CB) products have gained popularity among the public. The anti-inflammatory properties of CBs have piqued…
Efficacy of Dronabinol for Acute Pain Management in Adults with Traumatic Injury: Study Protocol of A Randomized Controlled Trial
Abstract Delta-9-tetrahydrocannabinol (Δ9-THC) and other cannabinoids present in cannabis (marijuana) have been shown to affect the normal inhibitory pathways that…
Sex- and Gender-Based Analysis in Cannabis Treatment Outcomes: A Systematic Review
Abstract There is evidence that sex- and gender-related factors are involved in cannabis patterns of use, health effects and biological…