Pyrazolyl-Ureas as Interesting Scaffold in Medicinal Chemistry
Abstract The pyrazole nucleus has long been known as a privileged scaffold in the synthesis of biologically active compounds. Within…
protein kinase inhibitors
The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities
Abstract DYRK (dual-specificity tyrosine-regulated kinases) are an evolutionary conserved family of protein kinases with members from yeast to humans. In…