Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter
Abstract The sodium iodide symporter (NIS) functions to transport iodide and is critical for successful radioiodide ablation of cancer cells.…
protein homeostasis
S-Glutathionylation of human inducible Hsp70 reveals a regulatory mechanism involving the C-terminal α-helical lid
Abstract Heat shock protein 70 (Hsp70) proteins are a family of ancient and conserved chaperones. Cysteine modifications have been widely…